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Popularization of research advances on COVID-19

2021 - News Covid-19.info

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What type of immunity is the most effective?

Acquiring effective immunity is a key element in our fight against the virus. Good immunity gives robust and durable protection. However, there are two types of adaptive immunity against SARS-CoV-2: the first is natural immunity, acquired when infection with the virus takes place, and the other is vaccinal immunity. Their effect may even be cumulative. […]

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What after-effects one year after hospitalisation?

The COVID-19 pandemic remains a major problem for public health. It has infected more than 200 million people and there have been more than 4,3 million deaths. Post SARS-CoV-2 infection after-effects have already been reported, and this is becoming a matter for concern in view of the large number of cases. Until recently, 2 studies […]

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Challenges specific to the most advanced African countries

By March 2021, some African countries had suffered two waves of infection with a total of more than 2,9 million people affected and more than 74 000 deaths. As is the case in other parts of the world, the effects of the pandemic are extremely variable from one country to another. These variations may be […]

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Micro-droplets could be the most significant form of transmission

For a century now, scientists have believed that the main means of respiratory virus transmission is through droplets released by coughing or sneezing, which are deposited on the mucus membranes (eyes, nose or mouth) of a potential new host, or on a surface via which they can infect. These droplets can travel more than 1 […]

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CD4 T lymphocytes from endemic coronaviruses could activate

SARS-CoV-2 has numerous similarities with endemic human coronaviruses (HCoV), which cause common infections. Several studies suggest that anti-HCoV immunity exists, capable of combatting SARS-CoV-2, although its role in the physiopathology of COVID-19 is unclear. This cross-immunity is hotly debated, but in the light of its importance for vaccination, it is crucial to better understand its […]

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The origin of SARS-CoV-2 is still hotly debated

Since the first cases of COVID-19 in December 2019 in Wuhan, we have been trying to establish the origins of SARS-CoV-2. Currently, several hypotheses are being debated.    Firstly, did SARS-CoV-2 emerge from an animal reservoir (zoonosis)? A large majority of human viruses do, in effect, emerge from animal sources. Coronaviruses infect numerous species, including humans, […]

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The evolution of the pandemic in the United States during 2020

The United States was the country with the highest numbers of COVID-19  cases and deaths in the world in 2020. 3 waves of the epidemic followed in quick succession: the 1st in the springtime, after the virus first appeared in the country, affecting mainly urban areas; the 2nd during the summer, affecting mainly the south […]

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A broad-spectrum vaccine effective against sarbecovirus

SARS-CoV-2 is a member of the genus β-coronavirus and subgenus sarbecovirus. Other sarbecoviruses have already caused epidemics, such as SARS-CoV in 2003 (about 8 000 infections and 800 deaths) and MERS-CoV in 2012 (at least 2 600 cases and 900 deaths). Sarbecoviruses have spike surface proteins, the target of powerful neutralising antibodies, that differ while […]

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Targeting epitopes to improve vaccines

Obtaining a vaccine that works against COVID-19 has been one of the main priorities of recent times. Numerous candidate vaccines, using different technological platforms, have been developed. These vaccines, designed by expressing the SARS-CoV-2 spike surface protein, induce neutralising antibodies against this virus. However, the emergence of variants such as Alpha or Delta, that have […]

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