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Popularization of research advances on COVID-19

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Profibrotic macrophages could lead to respiratory distress

Around 5% of COVID-19 patients develop Acute Respiratory Distress Syndrome (ARDS), the mechanisms of which are still poorly understood. The development of non- COVID-19 cases of ARDS has 3 stages: damage to the alveolar barrier and the appearance of pulmonary edema, proliferation of epithelial cells to restore this barrier and, in some patients, a phase […]

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How does SARS-CoV-2 attack the olfactory system?

Anosmia or loss of smell is a common symptom of COVID-19. The mechanism of this phenomenom is poorly understood but some studies suggest that the olfactory nerves may serve as a pathway for SARS-CoV-2 to enter the brain. Studies on the olfactory mucosa and human olfactory bulbs have not advanced very far, since it is […]

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The COVID-19 pandemic has worsened problems of anxiety and depression

Mental illness has been a major public health concern across the world for several decades. Amongst its various forms, those recognised as being the most disabling are depressive and anxiety disorders. These illnesses affect men and women of all ages. Despite numerous campaigns to combat these problems, they have not lessened since the 1990s.  The […]

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Cellular senescence is a factor in pathology

SARS-CoV-2 causes infection of the upper respiratory passages causing respiratory disease or even multiple organ failure that can lead to death. These pathologies are a priori the result of over-activation of the immune system, known as a cytokine storm, rather than infection by the virus itself. The entry of a virus, SARS-CoV-2 for example, into […]

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Using artificial intelligence to predict the condition of patients

The aim of artificial intelligence (AI) is that machines are able to imitate real intelligence. Artificial neural networks are made up of computer servers capable of processing complex calculations from large databases. AI and the resulting processed data are dynamic, since the machine is constantly learning thanks to the algorithms developed by researchers. AI holds […]

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What after-effects one year after hospitalisation?

The COVID-19 pandemic remains a major problem for public health. It has infected more than 200 million people and there have been more than 4,3 million deaths. Post SARS-CoV-2 infection after-effects have already been reported, and this is becoming a matter for concern in view of the large number of cases. Until recently, 2 studies […]

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Are interferons an indicator of levels of severity?

Severe cases of COVID-19 are characterised by raised levels of pro-inflammatory cytokines in the blood circulation as well as by exacerbated inflammation. Interferons (IFN) are anti-viral cytokines which have been given particular attention. They are made up of 3 families: the IFN-I (⍺ and β), the IFN-II (ɣ) and the IFN-III (𝛌 1-4).  While we […]

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Long-COVID in the United States: the next health disaster scenario?

The majority of adults in the West are now vaccinated. This is the case in, for example, more than half of the adult population in the United States. Here, several preventative health measures, such as mask wearing and social distancing, have been relaxed to enable a return to near-normal life. However, the 10 to 30% […]

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SARS-CoV-2 increases the risks of heart attack

Since the beginning of the pandemic, more than 190 million people have been infected by SARS-CoV-2. The main risk for infected people is pneumonia, which can develop into acute respiratory distress with a high level of mortality. However, COVID-19 is a complex disease that can affect a number of different organs. It has been reported […]

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Rare severe cases in children

With the exception of babies, severe cases of COVID-19 occur mainly in adults. While they are liable to infection by SARS-CoV-2, children represent only 1,5% of hospitalisations. Unlike what we previously thought, they have a relatively limited role in the spread of SARS-CoV-2. They develop a complete and effective immune response after infection, as do […]

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