A broad-spectrum vaccine effective against sarbecovirus
SARS-CoV-2 is a member of the genus β-coronavirus and subgenus sarbecovirus. Other sarbecoviruses have already caused epidemics, such as SARS-CoV in 2003 (about 8 000 infections and 800 deaths) and MERS-CoV in 2012 (at least 2 600 cases and 900 deaths). Sarbecoviruses have spike surface proteins, the target of powerful neutralising antibodies, that differ while […]